What are chronic infections?

Infectious diseases that do not heal acutely but persist in the body for long periods and can flare up repeatedly.

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Definition

Subacute recurrent infections

By chronic infections we understand infectious diseases that do not heal acutely, but persist in the body for long periods and can flare up repeatedly (so-called subacute recurrent infections). Such infections often progress insidiously and can cause a variety of different symptoms in different organs - therefore they are often misinterpreted by the environment or even by doctors.

Zoonoses are not exotic exceptions. In our globalized world, they are the rule we often overlook.
Dr. Walter TarelloVeterinarian & Zoonosis Researcher
Pathogens

Examples of chronic infectious pathogens

Borrelia burgdorferi

high

Causative agent of Lyme borreliosis

Rickettsia species

high

e.g. causative agent of spotted fever and presumably involved in CFS

Babesia

medium

A protozoan, causes babesiosis - malaria-like symptoms

Bartonella

medium

responsible for cat scratch disease among others, can cause chronic fatigue

Ehrlichia/Anaplasma

medium

infect white blood cells, transmitted through tick bites

Chlamydia

medium

can trigger chronic inflammation, e.g. in joints

Mycoplasma

medium

e.g. Mycoplasma pneumoniae, can cause chronic respiratory complaints

Coxiella burnetii

medium

causative agent of Q fever, can become chronic

Borna Virus

low

controversial virus with neuropsychiatric symptoms

Epstein-Barr Virus (EBV)

high

remains in the body after initial infection, can trigger other diseases

Co-infections are the rule

Often chronically infected patients have multiple infections. Especially with tick-borne diseases, this is more the rule than the exception. A recent survey among patients with chronic Lyme disease found that over 50% of them have laboratory-confirmed co-infections - often with Babesia, Bartonella or Ehrlichia.

Why do these infections often remain undetected?

Chronic infections pose special challenges to medicine

Multisystem progression

Affect many organs simultaneously and mimic other diseases

The great imitator

Lyme disease is called this because symptoms are non-specific and mimic other diseases

Autoimmune-like symptoms

Can produce rheumatic complaints or multiple sclerosis-like symptoms

Inadequate tests

Standard laboratory tests often not sensitive enough, especially after acute phase

Seronegative Lyme disease

Antibody tests can be negative even though pathogens persist in tissue

The problem with routine medicine

Today's routine medicine has no clear diagnostic markers for post-Lyme syndrome (persistent symptoms after antibiotic therapy) and often no therapeutic concept - many patients are then treated with painkillers or antidepressants.

Our Philosophy

The whole person in focus

We consider the whole person and the entire complexity of the infection. Every chronic infection case is different - depending on the pathogen mix, immune status and other factors.

Chronic infections are curable, but only if they are perceived and treated in their complexity and interaction
Quote from our guidebook

Learn more about our main topics

In the following sections we dedicate ourselves to our two main topics in detail

Lyme Disease Infection (Lyme Borreliosis)

Comprehensive information about the "great imitator" and its complex symptoms

Learn More

CFS - Chronic Fatigue Syndrome

Understand the connections between infections and chronic fatigue

Learn More
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